If virtual NUMA is configured with vCpu hotplug settings, the virtual machine will be started without virtual NUMA and instead it will use Uniform Memory Access with interleaved memory access. The virtual machine log displays the message:
vmware.log> vmx| W110: NUMA and VCPU hot add are incompatible. Forcing UMA
There is no current solution. If you do not plan to use vCpu hotplug, do not enable it. Add the maximum vCpu’s that might be needed by the workload.
Source:VMware KB